Bioactive glycosides from the African medicinal plant Boerhavia erecta L.
نویسندگان
چکیده
Phytochemical studies of the previously unexplored stem of Boerhavia erecta from Burkina Faso, resulted in the isolation of an unreported glycoside 4, 2,3-dihydroxypropylbenzoate-3-O-β-[4″-methoxy] glucuronide as well as seven known glycosides (1-3, 5-8). The major isolate 5 and 8 indicated a significant inhibition against HIV integrase (IC50 10 and 22 μg/mL, respectively). The extracts and isolates were also tested for anti-malarial activity, but insignificant activity was observed.
منابع مشابه
Betacyanins and phenolic compounds from Amaranthus spinosus L. and Boerhavia erecta L.
Stem bark extracts of Boerhavia erecta L. (erect spiderling) and Amaranthus spinosus L. (spiny amaranth), two wild growing weed plants used in traditional African medicine, were characterized with respect to their phenolic profile including the betalains. While the main betalains in A. spinosus were identified as amaranthine and isoamaranthine, the major betacyanins in B. erecta were betanin, i...
متن کاملPhytochemical And Biological Importance of Boerhavia diffusa: A Plant of Ethnopharmacological knowledge
Abstract: Boerhavia diffusa (BD) and its other species have been assembled in this paper due to their enormous medicinal properties which hold tremendous influence on disease burden and affordability of health care. This paper enlightens mostly on the root part of this plant along with a number of bioactive rotenoid compounds and isolation of rotenoids from the roots of Boerhavia diffusa includ...
متن کاملBioactive flavone-C-glycosides of the African medicinal plant Biophytum umbraculum.
Three flavone-C-glycosides-cassiaoccidentalin A (1), isovitexin (2) and isoorientin (3)-were isolated from the ethyl acetate (EtOAc) soluble fraction of the methanol crude extract of the African medicinal plant Biophytum umbraculum, This is the first report of these compounds in this plant. All compounds were identified by spectroscopic analysis and comparison with published data. Isoorientin (...
متن کاملZebrafish bioassay-guided microfractionation identifies anticonvulsant steroid glycosides from the Philippine medicinal plant Solanum torvum.
Medicinal plants used for the treatment of epilepsy are potentially a valuable source of novel antiepileptic small molecules. To identify anticonvulsant secondary metabolites, we performed an in vivo, zebrafish-based screen of medicinal plants used in Southeast Asia for the treatment of seizures. Solanum torvum Sw. (Solanaceae) was identified as having significant anticonvulsant activity in zeb...
متن کاملFlavonoids from the leaves of Iranian Linden; Tilia rubra subsp. caucasica
Background and objectives: Plants belonging to the genus Tilia L. (Tiliaceae) are often tall beautiful trees which are considered for various medicinal potentials of their flowers and leaves. The present study was an attempt to investigate the phytochemical constituents of Tilia rubra subsp. caucasica leaves from the hyrcanian forests of north of Iran. Methods: Chroma...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Natural product research
دوره 29 20 شماره
صفحات -
تاریخ انتشار 2015